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stellarelli stellarelli
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6 years ago
Deficiency in the production of AIRE results in _____. (Select all that apply.)
 
  a. normal expression of tissue-specific proteins in the bone marrow and thymus
  b. incomplete negative selection of developing T cells
  c. the development of autoimmune B-cell and T-cell responses against endocrine glands and other tissues
  d. death in infancy
  e. the development of autoimmune polyendocrinopathycandidiasis ectodermal dystrophy (APECED).
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rosie_9800rosie_9800
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6 years ago
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