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Home Q & A Board Biology-Related Homework Help Medicine Immunology
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QiTian QiTian
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6 years ago
T-cell receptors do not undergo isotype switching. Suggest a possible reason for this.
 
  What will be an ideal response?
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6 years ago
T-cell receptors are not made in a secreted form, and their constant regions do not contribute to T-cell effector function. Other molecules secreted by T cells are used for effector functions. There is therefore no need for isotype switching in T cells, and the T-cell receptor loci do not contain numerous alternative C genes.
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