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bruin bruin
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8 years ago Edited: 8 years ago, bruin
Hi there,

I recently read this sentence in a book: "So what is important about 'junk' DNA? [...] much of the non-protein-coding DNA controls the expression of other genes."

Forgive my cluelessness about genetics but on the wikipedia page for transcription factors it lists the following types of molecules that can control gene expression:
  • transcription factors
  • coactivators
  • corepressors
  • chromatin remodelers
  • histone acetylases
  • deacetylases
  • kinases
  • methylases

And it also says that all of these molecules are proteins.

So can someone give me some examples of non-protein-coding DNA that nevertheless controls gene expression within the human genome? 
Post Merge: 8 years ago

Well, I feel kind of dumb - I think I just found the answer in another thread down the page.

The answer is that non-coding DNA can influence gene expression by transcribing RNA which then, instead of translating into a protein, binds to DNA or other RNA to control gene expression.  Is that it?

Still, can someone give me an example of RNA that regulates gene expression instead of translating into a protein?
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bio_manbio_man
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8 years ago
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