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emhen emhen
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9 years ago
Duchenne muscular dystrophy (DMD) is an Xlinked
recessive human disease affecting muscles. Six
small boys had DMD, together with various other
disorders, and they were found to have small deletions
of the X chromosome, as shown here:
a. On the basis of this information, which chromosomal
region most likely contains the gene for DMD?
b. Why did the boys show other symptoms in addition
to DMD?
c. How would you use DNA samples from these six
boys and DNA from unaffected boys to obtain an
enriched sample of DNA containing the gene for
DMD, as a prelude to cloning the gene?
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Educator
9 years ago
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