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stalmoney stalmoney
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6 years ago
Carbonic anhydrase has two substrates, carbon dioxide and bicarbonate, which are both converted to carbonic acid. Kinetic data for each is given below.
 
  While determining the kinetics of HCO3- as a substrate, how would the addition of CO2 effect the reaction if the rate were measured by the disappearance of bicarbonate?
 
  Substrate Km (mM) Kcat (sec-1) Kcat/Km (m M-1sec-1)
  CO2
  HCO3- 12
  26 1106
  4105 8.3104
  1.5104
   a. CO2 would increase the activity of the enzyme
   b. CO2 would cause an apparent decrease in the Km for HCO3-
   c. CO2 would act as a noncompetitive inhibitor
   d. CO2 would act as a competitive inhibitor
   e. none of the above
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NILLABRONILLABRO
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6 years ago
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