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JustGuilty JustGuilty
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6 years ago
In eukaryotes, there is a surveillance system that degrades nonfunctional mRNAs that contain termination codons in the coding region. Explain how mRNA degradation is coupled with translation.
 
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6 years ago
Ans: In nonsense-mediated mRNA decay, there is a degradation signal near the end of the mRNA that is masked when the mRNA is being translated. If there is a premature stop codon in the coding region, the ribosome dissociates and the degradation signal becomes accessible.
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