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WadeChl WadeChl
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7 years ago
When the RNA primers are removed from the 5' ends of eukaryotic chromosomes after replication, DNA polymerase is unable to fill in the gaps. What prevents the chromosomes from getting shorter and shorter with each round of replication?
 
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7 years ago
The enzyme telomerase maintains chromosome lengths by adding telomere repeats to the chromosome ends. Telomerase contains an RNA component that is complementary to the telomere repeat unit of the chromosome. After binding to the overhanging repeat, the telomerase RNA is used as a template to synthesize new chromosomal telomere repeats.
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