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hihihihihihi hihihihihihi
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6 years ago
During meiosis in a reciprocal translocation heterozygote, what are the three ways that chromosomes may segregate at anaphase I, and what are the consequences for the resulting gametes?
 
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6 years ago
In alternate segregation, alternate centromeres (from nonhomologous chromosomes) migrate to the same pole. This results in normal gametes, each having a complete set of genes (one half with all normal chromosomes and one half with translocated chromosomes). In adjacent-1 segregation, adjacent nonhomologous centromeres migrate to the same pole. This results in gametes with either duplications or deletions of genes, which are usually inviable. In adjacent-2 segregation, adjacent homologous centromeres migrate to the same pole. This also results in inviable gametes with duplications or deletions.
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