A woman affected with an X-linked recessive disorder:
A. Has one X chromosome affected by the mutation
B. Will transmit the disorder to all of her children
C. Will transmit the disorder to all of her sons
D. Will not transmit the mutation to any of her daughters
Question 2In creating your female patient's pedigree, you note that she and both of her sisters were affected by the same genetic disorder.
Although neither of her parents had indications of the disorder, her paternal grandmother and her paternal grandmother's two sisters were affected by the same condition. This pattern suggests:
A. Autosomal dominant disorder
B. Chromosomal disorder
C. Mitochondrial DNA disorder
D. X-linked dominant disorder
Question 3Which of the following are found in an individual with aneuploidy?
A. An abnormal number of chromosomes
B. An X-linked disorder
C. Select cells containing abnormal-appearing chromosomes
D. An autosomal recessive disorder
Question 4A woman with an X-linked dominant disorder will:
A. Not be affected by the disorder herself
B. Transmit the disorder to 50 of her offspring (male or female)
C. Not transmit the disorder to her daughters
D. Transmit the disorder to only her daughters
Question 5With an autosomal recessive disorder, it is important that parents understand that if they both carry a mutation, the following are the risks to each of their offspring (each pregnancy):
A. 50 chance that offspring will carry the disease
B. 10 chance of offspring affected by disease
C. 25 chance children will carry the disease
D. 10 chance children will be disease free
Question 6In autosomal recessive disorders, carriers have:
A. Two mutated genes; one from each parent that cause disease
B. A mutation on a sex chromosome that causes a disease
C. A single gene mutation that causes the disease
D. One copy of a gene mutation but not the disease
Question 7In autosomal recessive (AR) disorders, individuals need:
A. Only one mutated gene on the sex chromosomes to acquire the disease
B. Only one mutated gene to acquire the disease
C. Two mutated genes to acquire the disease
D. Two mutated genes to become carriers
Question 8When analyzing the pedigree for autosomal dominant disorders, it is common to see:
A. Several generations of affected members
B. Many consanguineous relationships
C. More members of the maternal lineage affected than paternal
D. More members of the paternal lineage affected than maternal