In the construction of a YAC library, each chromosome has the advantage of being

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In the construction of a YAC library, each chromosome has the advantage of being

In the construction of a YAC library, each chromosome has the advantage of being able to hold very long DNA sequences. However, besides selectable marker(s) the YAC vector must minimally include which of the following?
A) a bacterial origin (ori)
B) cos site(s) and origin
C) centromere, telomeres, and yeast origin
D) centromere and origin
E) centromere and telomeres

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