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Home Q & A Board Biology-Related Homework Help Cell Biology
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colleen colleen
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12 years ago
Describe the mode of action of the ?-lactam antibiotics.
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Sunshine ☀ ☼

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12 years ago
You mean beta-lactam antibiotics specifically target PBPs in bacterial cells. Bound transpeptidases (also called penicillin-binding proteins, or PBPs) are unable to cross-link peptide chains, so the result of beta-lactam antibiotics is a cell with a weak cell wall. Cells without linked cell wall peptides will eventually be lysed due to an inability to withstand osmotic pressure differences.
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