How are genes identified in a DNA sequence?
1.The ribonucleotide sequence that is complementary to the DNA sequence is determined, and from that the amino acid sequence is obtained.
2.The entire human genome encodes genes, so computer software scans for strings of bases that mark beginnings and ends of each.
3.Amino acid coding regions are separated by noncoding regions called ORFs, or open reading frames, that are detected by their characteristic base sequences.
4.Computer software scans sequences for identifiable strings of bases that mark splice sites and beginnings and ends of genes.4
Question 2Which choice best describes the main idea behind using the lod method to determine if genes are linked?
1.Linked genes that are farther apart are more likely to be separated by crossing over, so genetic map units are derived from recombination frequencies.
2.The lod score is the log10 of the ratio of the two probabilities that results are either consistent with linkage or that they are not.
3.Software is used to calculate the probability, or lod score, that the observed frequency of recombination is consistent with linkage.
4.One lod map unit is equal to a 10 frequency of recombination.
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