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AidenSmith AidenSmith
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6 years ago
Patients with an X-linked inherited disease called Hyper IgM (XHIGM) syndrome have a deficiency CD40 ligand, a protein found on the surface of T lymphocytes. Patients with XHIGM are unable to make the class switch between IgM and either IgA or IgG. From this information you could conclude that

a. B-cell production of IgM does not depend on the CD40 ligand.
b. the class switch between IgM and either IgA or IgG requires T cells.
c. the switch between membrane-bounded IgM and secreted IgM requires T cells.
d. Both a and b are correct.
e. Both b and c are correct.
f. all of the above
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igotubabeigotubabe
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6 years ago
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