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8.The following table contains DNA-sequence information compiled by Marilyn Kozak (1987). The data
Tho Truong
Tho Truong
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8.The following table contains DNA-sequence information compiled by Marilyn Kozak (1987). The data
9. The following table lists α-globin and β-globin gene sequences for the 12 nucleotides preceding the start codon and the first nucleotide following the start codon. The data are for 16 vertebrate globin genes reported by Kozak (1987). The sequences are written from -12 to +4 with the start codon underlined.
Gene Sequence
-12 start +4
α-Globin Family
Human adult AGAGAACCCACCATGG
Human embryonic CACCCTGCCGCCATGT
Baboon AAAGAACCCACCATGG
Mouse adult CAGGAAGAAACCATGG
Rabbit adult GAAGGAACCACCATGG
Goat embryonic TCAGCTGCCACCATGT
Duck adult GGAGCTGCCACCATGG
Chicken embryonic CTCTCCTGCACAATGG
β-Globin Family
Human fetal AGTCCAGACGCCATGG
Human embryonic AGGCCTGGCATCATGG
Rabbit adult AAAACAGACAGAATGG
Rabbit embryonic AGACCAGACATCATGG
Chicken adult CCAACCGCCGCCATGG
Chicken embryonic CCCGCTGCCACCATGG
Xenopus adult TCAACTTTGGCCATGG
Xenopus larval TCTACAGCCACCATGG
Use the data in the table to
a. Determine the consensus sequence for the 16 selected α-globin and β-globin genes.
b. Compare the consensus sequence for these globin genes to the consensus sequence derived from the larger study of 699 vertebrate genes in Problem 8.
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bio_man
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A month ago
Hi Tho,
I found this question from a textbook about genetics. Here's the question and its answer.
Part A
Part B
Does this help?
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