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A patient has been given a prescription for levodopa-carbidopa (Sinemet) for a new diagnosis of ...

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A patient has been given a prescription for levodopa-carbidopa (Sinemet) for a new diagnosis of ...

A patient has been given a prescription for levodopa-carbidopa (Sinemet) for a new diagnosis of Parkinson’s disease. The patient asks the nurse, “Why are there two drugs in this pill?” The nurse’s best response reflects which fact?

▸ Carbidopa allows for larger doses of levodopa to be given.

▸ Carbidopa prevents the breakdown of levodopa in the periphery.

▸ There are concerns about drug–food interactions with levodopa therapy that do not exist with the combination therapy.

▸ Carbidopa is the biologic precursor of dopamine and can penetrate into the central nervous system.

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Pharmacology and the Nursing Process

Edition: 9^th

Authors: Lilley, Collins, Snyder

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