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Home Q & A Board Biology-Related Homework Help Biochemistry
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Happyhuman001 Happyhuman001
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2 months ago
The question consists of a table in which the percentage of different bases of DNA molecule in a human are written like this:
Source of DNA.     %Adenine.      %Guanine.     %Thymine.     %Cytosine
       Human.                 30.9.                    19.9.                 29.4.                19.8
The question asks to find a pattern in the base ratios. According to me the pattern is that the percentage is increasing and decreasing simultaneously as we go from left to right of the row. Is this pattern correct? Or there is another pattern? Kindly tell.
Source  Biology for Cambridge AS & A level (written by Mary jones, Richard Fosbery, Dennis Taylor and Jennifer Gregory
Ch: 6 (Nucleic acids and protein synthesis
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bio_manbio_man
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2 months ago
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We apply Chargaff's rule:

Chargaff's rules state that in the DNA of any species and any organism, the amount of guanine should be equal to the amount of cytosine and the amount of adenine should be equal to the amount of thymine. Further a 1:1 stoichiometric ratio of purine and pyrimidine bases (i.e., A+G=T+C) should exist.

Notice that the percentage of adenine is nearly that of thymine, and the percentage of guanine is nearly that oc cytosine. Hence, we notice a ratio that is roughly one to one.

Does that help?
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#2
2 months ago
Thanks for answering. I have got the concept!
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