× Didn't find what you were looking for? Ask a question
Top Posters
Since Sunday
g
2
2
Home Q & A Board Biology-Related Homework Help Cell Biology
New Topic  
xask13 xask13
wrote...
Posts: 2
Rep: 0 0
10 years ago
What kind of signal sequence would transcription factors have?
Read 589 times
1 Reply

Related Topics

Replies
wrote...
#1
Educator
10 years ago
Did you meant what DNA sequence do transcription factors respond to?

Transcription factors are modular in structure and contain the following domains:

DNA-binding domain (DBD), which attach to specific sequences of DNA (enhancer or Promoter: Necessary component for all vectors: used to drive transcription of the vector's transgene promoter sequences) adjacent to regulated genes. DNA sequences that bind transcription factors are often referred to as response elements.

Trans-activating domain (TAD), which contain binding sites for other proteins such as transcription coregulators. These binding sites are frequently referred to as activation functions (AFs).

An optional signal sensing domain (SSD) (e.g., a ligand binding domain), which senses external signals and, in response, transmits these signals to the rest of the transcription complex, resulting in up- or down-regulation of gene expression. Also, the DBD and signal-sensing domains may reside on separate proteins that associate within the transcription complex to regulate gene expression.
New Topic      
Quick Reply
Bold
Italic
Underline
Strikethrough
Subscript
Superscript
Insert Math Equation
Font Name
Font Color
Align left
Center
Align right
Bullet list
Numbered list
Insert a horizontal rule
Insert a table
Insert a Quote
View source
Explore
Post your homework questions and get free online help from our incredible volunteers
  1225 People Browsing
Start New Topic Take the Tour CoursesNew Study Tools Topics Trending Browse by Textbook
Related Images
  
 115
  
 537
  
 141
Your Opinion
Previous poll results: Do you believe in global warming?