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barry barry
wrote...
Posts: 11630
12 years ago
How does the nucleotide excision repair (NER) system in E. coli work, and what kinds of DNA damage does it repair?
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wrote...
Staff Member
12 years ago
The NER system repairs thymine dimers and other serious distortions of the DNA helix. It is a system of four proteins (UvrA, UvrB, UvrC, and UvrD) that work in a complex to recognize a distortion in the DNA, make cuts on either side of the lesion, release the short single-stranded cut segment, and allow DNA polymerase and ligase to fill in the gap with new bases.
- Master of Science in Biology
- Bachelor of Science
barry Author
wrote...
12 years ago
Awesome, thanks man.
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