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barry barry
wrote...
Posts: 11630
11 years ago
Given the following aligned sequences

Sequence 1   ATA   TGT   ATA   AAA
Sequence 2   ATA   TGT   TTA   AAG
Sequence 3   ATC   TGT   ATA   AAA
Sequence 4   ATC   TGG   ATA   AAG,

identify any transitions and transversions as well as any synonymous and nonsynonymous substitutions.
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wrote...
Staff Member
11 years ago
First codon: A to C: transversion, synonymous substitution (Ile - Ile)
Second codon: T to G: transversion, nonsynonymous substitution (Cys - Trp)
Third codon: A to T: transversion, nonsynonymous substitution (Ile - Leu)
Fourth codon: A to G: transition, synonymous substitution (Lys - Lys)
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