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Home Q & A Board Biology-Related Homework Help Cell Biology
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oanh.nguyenh oanh.nguyenh
wrote...
11 years ago
I'm reading an article for Parasitology and ran into this... here's the context:"GP63, also known as the major surface protease (MSP), has been related to resistance to complement-mediated lysis, among others."
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#1
11 years ago
Complement is part of the innate immune system. Antigen binds IgM or IgG, bound immunoglobin binds and activates the first complement protein complex, activated complement ultimately assembles a membrane attack complex on the surface of whatever the antigen is connected to and bores a hole through the membrane. No doubt a protease on the surface could interfere with the membrane attack complex.

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