relationship between transition-state analog and induced-fiy model?

Transition state analogs (transition state analogues), are chemical compounds with a chemical structure that resembles the transition state of a substrate molecule in an enzyme-catalyzed chemical reaction. Transition state analogs usually do not undergo a chemical reaction and can act as enzyme inhibitors by blocking their active site.

Like all catalysts, enzymes work by increasing the chemical reaction rate by stabilizing a high energy transition state intermediate which lowers the activation energy of the reaction. Transition state analogs that mimick this high-affinity intermediate but that do not undergo the catalyzed chemical reaction can therefore bind much stronger to an enzyme than simple substrate or product analogs.