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Home Q & A Board Biology-Related Homework Help Genetics and Developmental Biology
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selfstudy selfstudy
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11 years ago
Explain three ways someone can manifest an Autosomal Dominant phenotype when his father didn't have it.
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#1
11 years ago
Hi, a good example of autosomal dominant is the Huntington's disease. Autosomal dominant occurs when the mutation happens in one copy of a gene, even when the other copy is normal.

I'd look up the disease to figure out how people get it.
selfstudy Author
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#2
11 years ago
Thank you, but the question is actually about Huntington's. I'm looking for what can cause the autosomal dominancy.
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#3
11 years ago
Hmm, I see. Well, if one parent is heterozygous for the disease-associated allele, 50% of their offspring will have the disorder. If one parent is homozygous for the disease-associated allele, all their offspring will have the disorder. Autosomal dominant disorders often occur in every generation.
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