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Home Q & A Board Biology-Related Homework Help Cell Biology
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rkoch rkoch
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11 years ago
Which one of the following players in the E. coli DNA mismatch repair system possesses the ability?
Which one of the following players in the E. coli DNA mismatch repair system possesses the ability to hydrolyze a phosphodiester linkage in a molecule of deoxyribonucleic acid? [Note: remember that to be a correct answer to the question, the option must satisfy all of the conditions of the question.]


Methylase
Exonuclease
MutS
DNA polymerase I
Ligase


explain pls!
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wrote...
#1
11 years ago
Methylases add a methyl group to a particular site in a strand of DNA. Involved in finding the mismatch but no repair activity.
MutS is a targeting molecule for DNA repair but does not act in the actual repair process (directly anyway).
DNA Pol I adds the correct base in the repair process.
Ligase reties the DNA strand after repair.
Exonuclease is your answer. It does the actual cutting out (hydrolyzing) of the mismatched base.

They are all involved in the repair process though, hence the note:)
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