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boowoo1234 boowoo1234
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7 years ago
Some inhibitory postsynaptic potentials (IPSPs) are the result of Cl- entering the cell through a chloride channel. Other IPSPs are caused by the opening of K+ channels. How could movement of the potassium ion result in hyperpolarization of the postsynaptic cell?
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Educator
7 years ago
Hyperpolarization occurs when certain neurotransmitters inhibit the transmission of nerve impulses. They achieve this in two ways:

a. Opening of chloride ion channels       and/or     b. opening of potassium channels

* If opening of the channels occurs, it increases the membrane potential by allowing the negatively changed chloride ions into the cell and/or pumping the positively charged potassium ions out of the cell

For example, the neurotransmitter GABA binding to GABAB receptors opens potassium channels. This leads to hyperpolarization as it counteracts excitatory signals tha tmay arrive at the neuron.

to be concise, hyperpolarization occurs when the negative charge inside the neuron (axon) increases. Pumping the potassium ions out increases the negative charges inside the cell and leads to hyperpolarization (the potential from -70 mV becomes -80 mV)
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