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Home Q & A Board Biology-Related Homework Help Biochemistry
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elnerdo elnerdo
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10 years ago
Describe how a linear sequence of amino acid give rise to the 3D structure of proteins. Detail the significance of their structure how it may be modified and results of the modification?
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#1
10 years ago
The three-dimensional conformation of a protein molecule is determined by its amino acid sequence. The folded structure is stabilized by noncovalent interactions between different parts of the polypeptide chain. The amino acids with hydrophobic side chains tend to cluster in the interior of the molecule, and local hydrogen-bond interactions between neighboring peptide bonds give rise to α helices and β sheets.
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#2
10 years ago
It 1st starts out as a primary structure, which is a string of amino acids, then the secondary structure forms. This happens when adjacent amino acids form hydrogen bonds with each other, forming alpha helices and beta pleated sheets. Then the tertiary structure (which is the 3-D shape) formed by disulfide bonds.

A lot of it can be found here: http://www.ncbi.nlm.nih.gov/books/NBK26830/ Sad Dummy
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