Top Posters
Since Sunday
5
o
5
4
m
4
b
4
x
4
a
4
l
4
t
4
S
4
m
3
s
3
New Topic  
lavashooter3 lavashooter3
wrote...
Posts: 7
Rep: 0 0
6 years ago
Using recombination frequency to map genes relative to each other is a powerful tool in genetics. A major limitation, however, is that Genetic Distance has an upper limit (i.e. one cannot establish linkage for genes that are more than 50 cM distant). Please discuss/describe this limitation. Why is there a limit? What does it mean?
Read 207 times
2 Replies
Replies
wrote...
6 years ago
Genetic frequency /recombination frequency, recombination is the one of the key evolutionary shaping the architecture of the genome, it involves the rearrangement of the genetic material it joins the perilously unassociated DNA fragments is often acomplished by the breaking and rejoining of DNA fragments.

There will be four types of recombinations one is homolougs, heterologous, site specific , transposition. Recombination frequencies can be used for the map the position of the loci on a linear linkage group ,the order of the genes and relative distance between them in a linkage group corresponds to their order and relative distance on the chromosome .

At a very small distance recombination very rarely occurs, this leads to the generation of offspring only with type parental type .

At very large distance recombination occurs very frequently ,this leads to production more recombinants and there by leading to loss of the parental genotype this act as a major limitation of the genetic frequencies .frequent cross overs occur.

[See attachment]

I hope this helps Face with Cold Sweat
 Attached file 
Thumbnail(s):
You must login or register to gain access to this attachment.
Answer accepted by topic starter
bio_manbio_man
wrote...
Valued Member
Educator
Top Poster
Posts: 33224
6 years ago
Sign in or Sign up in seconds to unlock everything for free
This verified answer contains over 180 words.
1

Related Topics

New Topic      
Explore
Post your homework questions and get free online help from our incredible volunteers
  851 People Browsing
 108 Signed Up Today
Related Images
  
 4
  
 21
  
 249
Your Opinion
What's your favorite coffee beverage?
Votes: 274