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Home Q & A Board Biology-Related Homework Help Cell Biology
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ezpb567 ezpb567
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9 years ago
comparing the development of B and T cells from hematopoiesis to maturity.
(1) What are the B and T cells lineage specific molecules?
(2)What features ensure that both  T and B cells are mature and competent to interact with antigen?
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#1
Staff Member
9 years ago
Quote from: ezpb567 (9 years ago)
(1) What are the B and T cells lineage specific molecules?

Not making sense to me, "lineage specific molecules".

Quote from: ezpb567 (9 years ago)
(2)What features ensure that both  T and B cells are mature and competent to interact with antigen?

They go through clonal selection.

The clonal selection theory can be summarized like this:

  • Each lymphocyte bears a single type of receptor with a unique specificity (by V(D)J recombination).
  • Receptor occupation is required for cell activation.
  • The differentiated effector cells derived from an activated lymphocyte will bear receptors of identical specificity as the parental cell.
  • Those lymphocytes bearing receptors for self molecules will be deleted at an early stage.
What are the steps involved in B cell activation?

Make sure to watch: [Animation] - Clonal Selection
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