× Didn't find what you were looking for? Ask a question
Top Posters
Since Sunday
r
4
L
4
3
d
3
M
3
l
3
V
3
s
3
d
3
a
3
g
3
j
3
New Topic  
faraz faraz
wrote...
14 years ago
What specific cytoskeletal protein has its function altered as the ultimate effect of digitalis?
Read 1681 times
2 Replies

Related Topics

Replies
wrote...
Educator
14 years ago Edited: 14 years ago, bio_man
What course is this for?

I would say alpha-adducin

Moreover, Digitalis also disrupts cytoskeletal functions by inhibiting alpha-tubulin polymerization into microtubules!
wrote...
Staff Member
14 years ago
Faraz:

Digitalis alkaloids: Na+/ K+-ATPase inhibitors => intracellular Na+ raises => Na+/Ca2+ exchange less efficient => Ca2+ intracellular increases => stronger contractions

high intracellular Ca2+ ions can inhibit the assembly of microtubules (tubulin being the major component of cytoplasmic microtubules) and, therefore, play a role in the regulation of microtuble formation.

Makes sense?
- Master of Science in Biology
- Bachelor of Science
New Topic      
Explore
Post your homework questions and get free online help from our incredible volunteers
  2057 People Browsing
Related Images
  
 256
  
 1000
  
 405
Your Opinion