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Home Q & A Board Biology-Related Homework Help Genetics and Developmental Biology
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ceybe ceybe
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6 years ago
Imagine that you are searching for the gene associated with nail-patella syndrome, a dominant genetic disorder that causes developmental abnormalities. In a large pedigree, you discover an association between nail-patella syndrome and a genetic marker that occurs in two different alleles, A and B. Fifteen individuals within this pedigree have nail-patella syndrome and are A/B heterozygotes for the marker. Thirty individuals within this pedigree don't suffer from nail-patella syndrome and are homozygous for the A marker allele. One individual within this pedigree has nail-patella syndrome and is also homozygous for the A marker allele. The most likely explanation for this exceptional individual is
A) a new mutation converted the disease-causing allele to the wild-type form.
B) a new mutation converted the B allele of the marker to the A form.
C) the exceptional nail-patella individual is haploid.
D) recombination occurred between the nail-patella gene and marker gene in one of the parents of the exceptional individual.
Textbook 
Biological Science, Canadian Edition

Biological Science, Canadian Edition


Edition: 2nd
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ShadiasShadias
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6 years ago
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ceybe Author
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Helped a lot
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Thanks for your help!!
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