Which membrane transport process(es) is/are abnormal in people with cystic fibro

Active transport of chloride is impaired, in the airways, sweat glands, and pancreas. The affected epithelia are involved in production of sweat and mucus. Thus the respiratory, integumentary, and digestive systems are affected. Treatments include replacement of pancreatic digestive enzymes, which are blocked from secretion by the mucus buildup in secretory ducts, and respiratory therapies to loosen mucus in the airways and treat recurring infections. Gene therapy is being explored as well. Median survival is 37 years as of the publication date of the textbook. Causes of death can be related to malnutrition and respiratory illness. This is a genetic disease, in which the gene coding for the chloride transporter is abnormal.