Glycogenesis & Glycogenolysis

paralucia

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11 years ago

Glycogenesis & Glycogenolysis

Briefly explain the process of Glycogenesis & Glycogenolysis

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Sener

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11 years ago

Glycogenesis is the process of glycogen synthesis, in which glucose molecules are added to chains of glycogen for storage. This process is activated during rest periods following the Cori cycle, in the liver, and also activated by insulin in response to high glucose levels, for example after a carbohydrate-containing meal.

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paralucia Author

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11 years ago

Thanks Sener.

Although i found a different answer Confounded Face

Could you or someone confirm which one is correct?

Glycogenesis process - glucose is phosphorylated in glucose 6 phosphate by hexokinase, it is then converted into glucose 1 phosphate then uridine diphosphate glucose and finally into glycogen.

Glycogenolysis process - glucose is split off glycogen vis phosphorylation, glucose 1 phosphate is formed, glucose 1 phosphate is converted into glucose 6 phosphate then into glucose

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padre

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11 years ago

Sounds correct.

Glycogenesis is the formation of glycogen (GENESIS=beginning)
Glycogenolysis is the breakdown of glycogen to glucose (LYSIS=splitting).

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Tralalalala Slight Smile

paralucia Author

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11 years ago

thanks, i hope so!

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ehd123

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Valued Member

11 years ago

Yep I agree too, they both seem correct.
Keep in mind that gluconeogenesis is the reverse of glycolysis with the same enzymes except at like 3 steps or something. There are a few steps that have different enzymes simply because they may not be found in the cytosol.
I posted some charts that summarize both reactions, with their enzymes and structures, and compare and contrast the 2 pathways..

Hope this helps Slight Smile

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padre

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B.Sc in Biology
M.Sc Neuroscience
PhD. Candidate in Neuroscience

paralucia Author

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11 years ago

Great, thanks for the help ehd123 i really appreciate it.

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ehd123

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Valued Member

11 years ago

Anytime

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B.Sc in Biology
M.Sc Neuroscience
PhD. Candidate in Neuroscience

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