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jessicawcu jessicawcu
wrote...
Posts: 22
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10 years ago
When the ratio of insulin to glucagon is >1, which is the following is true with regards to fatty acid synthesis?

 
-malonyl CoA will inhibit carnitine palmitoyl transferase 1
-citrate levels will be low in the cytosol
-acetyl CoA carboxylase will be dephosphorlated and inactivated

I think malonyl CoA will inhibit carnitine palmitoyl transferase 1 is correct, what do you think?
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Staff Member
Educator
10 years ago
Note that this reaction is an energy requiring process (1 ATP per Malonyl-CoA formed). Acetyl-CoA carboxylase is an interesting enzyme. Studies of the enzyme from birds and mammals indicate that it forms long linear polymers.

-malonyl CoA will inhibit carnitine palmitoyl transferase 1
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