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SlideshowReport

Zinc fingers

Description
a. The transcription factor TFIIIA binds to the 5S RNA gene via zinc fingers inserted into the major groove.

The two major recognition regions, A block and C block, are contacted by fingers 7–9 and 1–3, respectively.

b. Structure of a zinc finger.

The structure shown is for a synthetic polypeptide with sequences found in a zinc finger protein.
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