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Subunits of the DNA Polymerase III Holoenzyme

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Subunits of the DNA Polymerase lll Holoenzyme Subunit Function 01 5'—3l polymerization e 3’—5’ exonuclease 0 Core assembly 7 5 Loads enzyme on 5/ template (serves as X clamp loader) U fl Sliding clamp structure (processivity Factor) 7' Dimerizes core complex Groupings Core enzyme: Elon- gates polynucleotide chain and proofreads 1/ complex
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