The consequences of crossover in the inversion loop in paracentric inversion heterozygotes

I I \ / ~ Crossover between / \ homologs /’ Anaphase I \ / mrgratron \ Dicentric \ Acentric chromosome Anaphasel chromosome migration yrAnaphasoI \ \ homolog separation / Dicentric 1 1 bridge 1 1. Lost 2 2' Random breakage Acentnc fragment rs lost due to lack of a cmtrormro; docmtnc fragment randomly breaks due \ to centromem mgralim. 3. W0 1 I :WME‘EEEQ t 1aiiiilililiiiib1'NormaI chromosome (viable) 2 a Detetion products 4 _ (nonviable) 3 -— 3’ 'nversion chromosome (viable) Crossover m the invemon loop results on two Viable gametes and 1 two nonvrable gametes.