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Oncogenes and Overactive EGF Receptors

Description
An oncogene. In this section of human breast tissue, phosphorylated
EGF receptor is stained brown. Normal cells are the ones with lighter staining. The
heavily stained cells have formed a neoplasm; the abnormal overabundance of the
phosphorylated EGF receptor means that mitosis is being continually stimulated in
these cells. The EGF receptor is overproduced or overactive in most neoplasms.
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