Concordance Values for Common Medicaland Behavioral Conditions in Humans

Table 19.3 Concordance Values for Common Medical and Behavioral Conditions in Humans Trait Percent Concordance MZ Twins DZ Twins Medical Conditions with Likely Genetic Influence Cleft lip 40 4 Club foot 30 Congenital hip dislocation 35 3 Epilepsy 60 20 Multiple sclerosis 30 Pyloric stenosis 25 3 RheumatOIdarthntis 35 Medical Conditions Unlikely to Have Strong Genetic influence Handedness (left and 79 77 right) Heart attack (both sexes) 37 20 Behavioral Conditions with Likely Genetic influence Bipolar disordera 40-60 8—1 0 Schizophreniab 35—75 10—28 Autism spectrum 60—82 10—25 disorderc'd aSmoller, J. W., and C. T. Finn. 2003. Am. J. Med. Genet. 123C: 48. bSullivan, P. F., et al. 2003. Arch. Gen. Psychiatry 6021 187. C Hallmayer, J., et al. 2011. Arch. Gen. Psychiatry 68:1095. dFoIstein, S., and M. Rutter. 1977. J. Child. Psychol. Psychiatry 18:297.