Genetics and Developmental Biology

KFC franchise

KFC franchise

As the owner of a KFC franchise, you want to raise chickens that have an extra set of wings.  How would you do it?  Be brief. 

ppk   3087   3 Replies

kong

Blastula stage

Blastula stage

All non-mammalian embryos go through a blastula stage with a fluid-filled blastocoel.  What function/s does/do the blastocoel serve in development of the frog embryo? 

ppk   1315   2 Replies

ppk

Pufferfish (FUGU)

Pufferfish (FUGU)

The pufferfish is, obviously, a fish, and a member of the vertebrate class of animals, as we are.  The complexity of the human genome is about 3,000 megabases (Mb), while that of the pufferfish is about 400 Mb.  Which two of the following r

ppk   1146   5 Replies

bio_man

Briefly describe an experiment you could do to provide convincing evidence

Briefly describe an experiment you could do to provide convincing evidence

Briefly describe an experiment you could do to provide convincing evidence that a specific gene called Dax-1, found on the X chromosome, is required for female primary sex determination. Also include a logical explanation for why males, who have a co

ppk   1376   1 Reply

bio_man

Analysis of a human female fetus by amniocentesis

Analysis of a human female fetus by amniocentesis

Analysis of a human female fetus by amniocentesis indicates that the baby will have a normal XX karyotype but is heterozygous for a mutation that inactivates the Xist promoter.  Explain how dosage compensation will be affected by this mutation.&

ppk   1590   2 Replies

ppk

autonomous or non-autonomous cell

autonomous or non-autonomous cell

Suppose you were to carry out a mosaic analysis of the EGFR homolog let-23, using a homozygous let-23(-) strain that carries a small free duplication including the let-23(+) gene.  The duplication is occasionally lost during somatic development,

ppk   1661   1 Reply

bio_man

Mammalian ES

Mammalian ES

Mammalian ES cells grown in culture on a “feeder” layer of fibroblasts can be made to differentiate into several types of differentiated cells by treatment with appropriate growth factors, but the feeder layer is essential.  What are two possibl

ppk   1015   1 Reply

bio_man

Gene Therapy Department Question

Gene Therapy Department Question

It is 2011, and you are doing your internship in the Gene Therapy Department of a well known medical school.  Techniques for gene therapy are now well established.  Hilary Clinton, midway through her first term as president, and her adminis

ppk   1010   1 Reply

bio_man

Drosophila patterning

Drosophila patterning

In experiments on Drosophila patterning, you treat fertilized eggs with a drug that completely blocks RNA polymerase II, which is required for all mRNA synthesis.

Explain briefly if and how you would expect this treatment to affect the pr

ppk   1045   1 Reply

bio_man

Steroid hormone testosterone

Steroid hormone testosterone

The steroid hormone testosterone controls almost all aspects of male development in mammals.  We know there is only a single type of testosterone receptor in all the cells that respond to it, because mutant XY individuals who lack the receptor a

ppk   1221   1 Reply

bio_man

Myosin heavy chain

Myosin heavy chain

In an animal that has only a single myosin heavy chain (MHC) gene, striated skeletal muscle contains an isoform of MHC that is not found in smooth muscle, which contains a different isoform not found in skeletal muscle. (Isoforms: very similar protei

ppk   1320   1 Reply

bio_man

Flies that expressed hunchback

Flies that expressed hunchback

Briefly describe the strains that were used to generate the flies that expressed hunchback (hb) in the anterior at a time when it is normally downregulated (during cellularization).  Don’t forget to mention how they targeted the hb expression.

ppk   1235   1 Reply

bio_man

symbiotic relationship

symbiotic relationship

Describe the types of symbiotic relationships seen between humans and bacteria. Give specific example for each type of relationship.

Chris   4200   1 Reply

bio_man

In human embryo, does the middle ear have an ectodermal or mesodermal origin?

In human embryo, does the middle ear have an ectodermal or mesodermal origin?

in human embryo, does the middle ear have an ectodermal or mesodermal origin ?

also if anyone has links to websites with videos or detailed pictures of the different steps in echinoderms, amphibians, birds and mammals embryogenesis plz po

karim89   3093   4 Replies

bio_man

Embyronic Stem Cells Q.

Embyronic Stem Cells Q.

As the first step in generating a ? -catenin knock-out mouse, you have used ES cells from a black mouse strain and selected for cells in which an appropriate transfected construct has undergone homologous recombination at the ?-catenin locus.  Y

ThePsychic   1521   2 Replies

ThePsychic

Homework Problem!

Homework Problem!

This is for my developmental biology class...

Fugu is a vertebrate like humans, with many of the same complex structures and organ systems. However, unlike humans the size of the Fugu genome is a mere 400 Mb compared to the 3000 Mb of huma

barry   3912   3 Replies

ThePsychic