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Home Q & A Board Biology-Related Homework Help Biochemistry
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daughterofzion daughterofzion
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12 years ago
A specific substrate will have a complementary binding site. When it binds with an enzyme, the formation 'changes', and as a result the bond breaks,leaving the substrate as separate product molecules.

What brings on the 'change' when the substrate and the enzyme combine?
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zzz
wrote...
#1
12 years ago
The change is simply a chemical reaction. Enzymes are nothing but biological catalysts which bring about a chemical reaction to give a product without changing themselves. Thus almost all biological reactions are enzyme catalysed ones. This speeds up a chemical reaction which would have taken place even in the abscence of the enzyme but at a much slower rate.. Thus, the 'change' is nothing but a chemical reaction when the substrate and the enzyme combine.
wrote...
#2
12 years ago
Binding site or active site of an enzyme has reactive groups that aid in chemical reaction. e.g. H2O might be added across the bond and hydrolysis will take place. Similar manner other groups bring about other changes and substrate is converted to a product.
wrote...
#3
12 years ago
The change in conformation resulting from the combination of the substrate and the enzyme is just the result of the chemical interaction between the two compounds.  When a new compound is introduced to the enzyme, the bonds created alter the electron distribution among the species, and each bonded atom must adjust (if necessary) to be able to find the lowest energy conformation possible.
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