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Home Q & A Board Biology-Related Homework Help Genetics and Developmental Biology
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lemon09 lemon09
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11 years ago
Suppose you identify a new gene in mice. One of its allels specifies white fur, another specifies brown. You want to see if the two interact in simple or incomplete dominance. What sorts of genetic crosses would give you the best answer??
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ILoveGodILoveGod
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11 years ago
1.  Obtain individuals of true breeding strains of both phenotypes.
2.  Do white x brown.
3.  Have a look at the resultant offspring ("the F1 generation").  If all the offspring are white, then it's simple dominance with the W allele as dominant.  If all the offspring are brown, then it's simple dominance with the B allele as dominant.  If the offspring have white hairs mixed with brown hairs, then it is codominance.  If all the offspring are all some color that is neither white nor brown (likely something intermediate between them) then it is incomplete dominance.
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11 years ago
If you took two individuals, one homozygous for brown (which I'll call BB) and the other homozygous for white (or a recessive that makes the coat white bb), and bred them you would have all of the resulting mice a light brown or brown and white throughout the coat, that would be the F1 generation. If you took two mice from the F1 generation and bred them, you would have a result out of four, one brown to two brown and white throughout the coat to one white. Out of four it would look like the following: BB, Bb, Bb and bb.
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