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country3313 country3313
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6 years ago
Match the definitions in questions 4-10 with the mast cell mediator (A-G) that most closely matches it.
 
  A. Histamine
  B. Tryptase
  C. Prostaglandin D2
  D. Leukotriene C4
  E. Platelet-activating factor
  F. Interleukin-5
  G. Tumor necrosis factor-Membrane phospholipid derivative that causes bronchoconstriction, retraction of endothelial cells, and relaxation of vascular smooth muscle
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6 years ago
ANS: E. Platelet-activating factor (PAF) is synthesized after mast cell activation by acylation of a membrane phospholipid derivative; it acts on bronchial smooth muscle cells and endothelial cells. Genetic deficiency of an enzyme that inactivates PAF is associated with asthma.
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