In mice, three mutant traits were investigated: snubnose, pintail, and a trait called jerker (a defect in motor skills). True breeding mice were crossed to generate F1 mice that were heterozygous for all traits (they were all pintail), and were then test crossed. The progeny of those were:
560 Jerker, snubnose, pintail
104 normal movement, normal nose, pintail
77 jerker, normal nose, normal tail
102 jerker, snubnose, normal tail
9 normal movement, snubnose, normal tail
548 normal movement, normal nose, normal tail
71 normal movement, snubnose, pintail
11 jerker, normal nose, pintail
a) Create and assign gene names according to the standard convention for gene nomenclature (three letter gene symbol).
b) Write out the genotypes of both the P1 and the F1 generations. Diagram these using parallel lines, each line representing a chromosome, with the loci indicated in position with the gene names you assigned.
c) Draw a genetic map that describes the map distance between these three genes. Use the proper formula (s) to determine the distance for ALL genes.
d) Calculate interference. What does the amount of interference mean from a biological perspective?
(I have also attached the word document if you can't see it properly here).
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