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Runner343 Runner343
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6 years ago
Which two classes of antidysrhythmic drugs have nearly identical cardiac effects?
 
  a. Beta blockers and calcium channel blockers
  b. Beta blockers and potassium channel blockers
  c. Calcium channel blockers and sodium channel blockers
  d. Sodium channel blockers and potassium channel blockers
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wrote...
6 years ago
ANS: A
Calcium channel blockade has the same impact on cardiac action potentials as does beta blockade, so these agents have nearly identical effects on cardiac function; that is, they reduce automaticity in the SA node, delay conduction through the AV node, and reduce myocardial contractility. Potassium channel blockers act by delaying repolarization of fast potentials. Sodium channel blockers block sodium channels to slow impulse conduction in the atria, ventricles, and His-Purkinje system.
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