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6 years ago
A 60-year-old female patient has begun taking a daily bisphosphonate to prevent osteoporosis and complains of gastrointestinal (GI) upset and dyspepsia. The primary care NP's initial response should be to:
 
  a. prescribe a proton pump inhibitor (PPI).
  b. order intravenous (IV) bisphosphonates.
  c. suggest that she take the drug with food.
  d. review the instructions for taking the drug with the patient.
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6 years ago
D
Oral bisphosphonates must be taken on an empty stomach, and the patient must remain upright and not eat or drink anything for 30 to 60 minutes. GI upset and dyspepsia are frequent and can be minimized with correct administration. A PPI is not indicated. IV bisphosphonates may be indicated if the patient is unable to tolerate the oral drug after correct administration is confirmed. Bisphosphonates should not be taken with food.
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