Gene Regulation

Rachel265

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9 years ago

Hello, I have some questions that were not answered previously and if you guys could give me some help that would be great! Thank you Slight Smile

1. Red blood cells do not live long and are made in the bone marrow. RBCs do not have a nucleus, but can generate more haemoglobin as needed. Give a hypothesis as to how this is possible.
2. A mutation is found in the gene that codes for the Lacl repressor protein gene. The protein no longer performs its intended function. Explain what would be the outcome at the gene level and for the E coli.
3. Explain how the work of Jacob and Monod was significant in understanding gene regulation.

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bio_man

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Educator

9 years ago

Quote from: Rachel265 (9 years ago)

1. Red blood cells do not live long and are made in the bone marrow. RBCs do not have a nucleus, but can generate more haemoglobin as needed. Give a hypothesis as to how this is possible.

The RBCs are denucleated to make space for the hemoglobin protein, so to carry more oxygen. They are only denucleated after the hemoglobin has been produced.

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Rachel265 Author

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9 years ago

Thank you very much! This helps a lot Slight Smile

If someone could answer number 2 and number 3 that would be greatly appreciated Slight Smile

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cjsalmonson

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9 years ago

Thank you

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bio_man

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Educator

9 years ago

Quote from: Rachel265 (9 years ago)

2. A mutation is found in the gene that codes for the Lacl repressor protein gene. The protein no longer performs its intended function. Explain what would be the outcome at the gene level and for the E coli.

With the repressor not working, the lac genes will be freely transcribed. The lac genes code for proteins involved in the breakdown of lactose in E.coli. Proteins are very complex and require a lot of energy to be made. If the lac proteins are always being made, even when unneeded, there will be a build up of these proteins and the cell will lose a lot of energy by constantly producing unneeded proteins.

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qwerty1997

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8 years ago

3. Explain how the work of Jacob and Monod was significant in understanding gene regulation.

The model proposed by Jacob and Monod that describes the way certain genes are either active or inactive, depending on whether there is a need for them to be active. The hypothesis is a prime example of effective and efficient biology at work, where resources are only used when needed.

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