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Home Q & A Board Biology-Related Homework Help Genetics and Developmental Biology
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panyaoha panyaoha
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10 years ago
DNA replication
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#1
Donated
Valued Member
10 years ago
ALL DNA replication is 5' to 3'.  On the lagging strand, Okazaki fragments are formed in small segments in the 5' to 3' direction, and are joined together with polymerase.
Pretty fly for a SciGuy
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#2
10 years ago
The helicase unzips the double-stranded DNA for replication, making a forked structure. The primase generates short strands of RNA that bind to the single-stranded DNA to initiate DNA synthesis by the DNA polymerase. This enzyme can work only in the 5' to 3' direction, so it replicates the leading strand continuously. Lagging-strand replication is discontinuous, with short Okazaki fragments being formed and later linked together.
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#3
Staff Member
10 years ago
It happens 5' to 3' on both the lagging and leading strand.
- Master of Science in Biology
- Bachelor of Science
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#4
Donated
10 years ago
In DNA Replication it occurs 5' to 3'


DNA replications needs a source of energy to proceed, this energy is gained by cleaving the 5'-triphosphate of the nucleotide that is added to the existing DNA chain. Any alternative polymerase mechanism needs to account for the source of the energy required for adding a nucleotide.
Success is not final, failure is not fatal: it is the courage to continue that counts. – Winston Churchill
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