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nc2012 nc2012
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6 years ago
Rb is a tumor suppressor gene; its normal function is to help restrain cell division. Loss of both copies of Rb is a causative factor in some kinds of cancer.
 
  You propose to treat these cancers by injecting the patients with a viral vector that carries a copy of the Rb gene and has the ability to infect all the cells of the body, thereby artificially driving expression of Rb in all the cells, including the cancer cells. Your colleague says NoYou'll simply kill the patient, because you will halt cell division throughout the body.
  A. Why would halting cell division throughout the body kill a full-grownadult person?
  B. Is your colleague right in thinking that forced expression of Rb in everycell will halt all cell division?
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PrincessAwesomePrincessAwesome
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6 years ago
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