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nhuynh0122 nhuynh0122
wrote...
6 years ago
Draw all reasonable structures, including their resonance forms, to indicate the possible position of the proton of HCl in thiamine chloride hydrochloride. Explain which of the structures you have drawn is most reasonable.
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wrote...
6 years ago
The external amino group is the least likely of the three possible sites of protonation since the lone pair on that group can resonate with the aromatic ring.

The lone pair on the ring nitrogen atoms cannot resonate into the ring and therefore they should be more basic.
nhuynh0122 Author
wrote...
6 years ago
Thank you so very much, was really helpful and kind of you to answer
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