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BonnienZip BonnienZip
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6 years ago
What is the function of the inverted repeat in the termination sequence of a rho-independent terminator? What would happen if a mutation occurred in this region?
 
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6 years ago
RNA polymerase transcribes the inverted repeat into the RNA transcript. As a result, a hairpin loop structure forms because of the complementarity of the inverted repeat regions. This hairpin is believed to aid termination by affecting the ability of RNA polymerase to continue elongation. If a mutation occurred in this region, termination would not be successful.
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