The negative side effects of non steroidal antiinflammatory drugs (NSAIDs) on the cardiovascular system are mediated by inhibiting which enzyme?
A. COX1
B. g-secretase
C. presenilin 1
D. COX2
E. adenylyl cyclase
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Question 2) The correct association between a drug and disease is:
A. -adrenergic receptor agonists with depression
B. Prozac with low blood pressure
C. Herceptin with metastatic colorectal cancer
D. Viagra with pulmonary arterial hypertension
E. Erbitux and Avastin with metastatic breast cancer
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Question 3) Which of the following is a correct pairing of an adult structure of the CNS and the primary brain vesicle from which it derives?
A. medulla and mesencephalon
B. cerebellum and mesencephalon
C. midbrain and mesencephalon
D. thalamus and telencephalon
E. cerebral cortex and rhombencephalon
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Question 4) A typical flow of information in a signal transduction pathway would be:
A. receptor G protein second messenger biological response
B. hormone second messenger GPCR biological response
C. hormone second messenger GPCR
D. hormone receptor second messenger GPCR biological response
E. GPCR second messenger biological response
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Question 5) Molecules that are produced by cells and act locally on other cells are called:
A. steroid hormones
B. receptors
C. paracrine hormones
D. phosphatases
E. iodothyronines
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Question 6) Intracellular fluid volume is normally what percent of body weight?
A. 60
B. 40
C. 20
D. 10
E. 5
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Question 7) Intravenous infusion of 2 L of which of the following solutions will lead to the largest increase in ICF volume?
A. D5W
B. isotonic NaCl
C. hypotonic NaCl
D. hypertonic NaCl
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Question 8) A 100 mmol/L solution of MgCl2 would be expected to have an osmolality of:
A. 50 mOsm/kg H2O
B. 100 mOsm/kg H2O
C. 200 mOsm/kg H2O
D. 300 mOsm/kg H2O
E. 350 mOsm/kg H2O
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Question 9) Osmosis is the:
A. active transport of water
B. number of solute particles in 1 kg of water
C. diffusion of water across cell membranes
D. defined as the weight of a volume of a solution divided by the weight of an equivalent volume of distilled water
E. amount of a substance relative to its molecular weight
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Question 10) A solution that causes a cell to shrink is:
A. isotonic
B. hypotonic
C. hypertonic
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